Cardiobacterium hominis pdf
We describe a 66-year-old woman with infective endocarditis due to Cardiobacterium hominis whose condi-tion, complicated by severe aortic regurgitation and congestive heart failure, necessitated aortic valve replace-ment despite treatment with ceftriaxone followed by ciproﬂoxacin. Investigations revealed infective endocarditis of prosthetic valve in mitral portion. hominis subtype IdA10G4 was observed for the current isolate, and phylogenetic analysis demonstrated that this particular isolate belonged to a novel C .
hominis is difficult as it grows very slowly and requires special enriched media for growth . Cardiobacterium hominis is a Gram-negative bacillus (rod-shaped) bacterium commonly grouped with other bacteria into the HACEK group. HACEK is an acronym for a group of organisms that are small, fastidious gram-negative bacilli.
In the present study, a consortium of Cardiobacterium hominis and Pseudomonas stutzeri was isolated from an effluent treatment plant of a textile industry, based on its ability to decolourise azo dyes including direct black 38 (DB38), a benzidine-based azo dye. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services.
This is a rare clinical presentation of isolated bacterial pericarditis by an atypical microorganism, without associated endocarditis. Cardiobacterium is a Gram-negative bacillus (rod-shaped) bacterium commonly grouped with other bacteria into the HACEK group. The case was complicated by an agranulocytosis after 3 weeks of antibiotic treatment induced by ceftriaxone. The microorganism was also isolated and identified using conventional methods (bacterial culture and biochemical tests) 17 days from the date of sample collection. A few weeks later, the patient presented with fever and infective endocarditis (IE) was diagnosed after the identification of vegetation on the aortic valve with transesophageal echocardiography. The genus Cardiobacterium consists of one species, Cardiobacterium hominis, originally designated “group II D organisms” until further described and named by Slotnick and Dougherty (1964).This organism is a fastidious, facultatively anaerobic, nonmotile, pleomorphic Gram-negative rod with a fermentative type of metabolism. Cardiobacterium hominis, a fastidious gram-negative bacillus rarely causing endocarditis, was isolated from blood culture of a 41-year-old man with subacute bacterial endocarditis.The patient had undergone an operation of valve replacement 4 years before.
Cardiobacterium hominis is considered as a member of the normal flora of the mouth and has been recovered from the nose or throat of normal individuals . Although the patient was young (a 17 year old man) and showed few of the characteristic features of the disease, the report does illustrate a number of the problems associated with this illness and highlights the need for the careful assessment of apparent culture negative endocarditis. A fifty-six-year-old Caucasian man with no significant past medical history was transferred to the tertiary care Health Sciences Centre Winnipeg, Manitoba from a peripheral hospital with new-onset congestive heart failure. SUMMARY: We report a new case of Cardiobacterium hominis endocarditis identified during an acute coronary syndrome. Cardiobacterium hominis Small Gram-negative rods and two tear-cells from an older culture (Gram stain).
This shareable PDF can be hosted on any platform or network and is fully compliant with publisher copyright. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. A patient with a congenital bicuspid aortic valve was initially seen with C hominis bacterial meningitis. However, it may also rarely cause endocarditis, an infection of the heart valves. Cardiobacterium hominis was first described in 1962 and was isolated from patients with endocarditis. History of dental treatment three months before illness with prophylactic antibiotic coverage. We postulate that infection-induced immune complex deposition in the skin led to their similar presentations.
These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. hominis can be recovered from currently availa-ble automated blood culture systems within the stand-ard incubation period of 5–6 days if the patient did not receive anti-microbial treatment, becauseC. Few cases of isolated septic arthritis in immunocompetent and immunocompromised adult patients had been described.
Cardiobacterium species have been described as Pasteurella-like organisms and are part of the microbiota in the nose, mouth, and throat and are present occasionally on other mucous membranes as well as in the gastrointestinal tract. Using these methods, Cardiobacterium hominis was identified in 2 days from the date of serum collection. Sign In; Create an Account "Never doubt that a small group of thoughtful, committed citizens can change the world. It is one of several bacteria that is normally present in the mouth and upper part of the respiratory tract such as nose and throat. It causes the majority of Gram-negative endocarditis cases and has an excellent prognosis and simple management if properly identified. All structured data from the file and property namespaces is available under the Creative Commons CC0 License; all unstructured text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. Despite the low virulence of the organism, major cardiac damage required valvular replacement, and there were multiple cerebral emboli with development of a mycotic aneurysm.
This UK SMI includes both biochemical tests and automated methods for the identification of microorganisms. In 1964, Slotnick and Dougherty (16) described the bacteria and gave it the current name. The study group included 49 patients (male-to-female ratio of 3.5:1) with a mean age of 48 years. To update information, we now present the largest biopsy-based clinicopathologic series on IE-associated GN.
homininis QRY with the species of Cardiobacter genus using nearly full 16S rRNA gene sequencing using the BIBI database. hominis from the respiratory tract in 68% of normalindividuals.Theinvestigationwascarriedout using specific fluorescent antibody technique and bacteriological culture. Abstract The clinical spectrum of disease caused by Cardiobacterium hominis, a small, gram-negative coccobacillus, is little known to physicians.From analysis of a new case of C hominis endocarditis on a fascia lata aortic valve, and from review of all previous reports of infection due to this microorganism, a remarkably consistent clinical picture emerged. Growth of the organism was only detected in 1 of 6 blood cultures after 7 days incubation. hominis infection in the squirrel monkey and, based on the observed genetic characteristics, confirms a new C . Three strains of Cardiobacterium hominis (31) were studied with the electron microscope.
On the other hand, prosthetic valve thrombosis (PVT) is a rare, but life-threatening condition that commonly occurs due to inadequate anticoagulation. We report a case of prosthetic valve endocarditis caused by Cardiobacterium hominis in a patient who had undergone atrial septal defect closure and mitral valve replacement of the heart in 1978. Cardiobacterium hominis endocarditis: two cases and a review of the literature Wong hkminis Chan 11 described a year-old man who presented with neurological signs and symptoms, including transient vertiginous attacks, intermittent vertical diplopia, slurring of speech, left-sided weakness face, arm and left incomplete homonymous hemianopia.
More recently, cases of fungal endocarditis have increased, particularly in postoperative patients, injection drug users, and immuno-compromised patients (4). is a fastidious, gram-negative coccobacillary organism which is one of three genera in the family . Alternative oral treatment with ciprofloxacin and rifampicin was successful, no surgical intervention was needed and homograft function could be preserved. Here, we provide a draft genome sequence of a pathogenic strain isolated from blood cultures of a patient with infectious endocarditis.
Cardiobacterium hominis endocarditis reported in the literature, but only few have been reported in children . Endocarditis caused by Cardiobacterium hominis was observed in a penicillin-allergic patient with a prosthetic cardiac valve who had received prophylactic therapy with erythromycin for dental extractions.